Management of Breast Cancer in Geriatric Patients

Geriatrics Breast cancer Treatment.

Authors

  • Tolga Canbak Health Science University, Umraniye Education and Research Hospital, Department of General Surgery, Istanbul, Turkey
  • Aylin Acar Health Science University, Umraniye Education and Research Hospital, Department of General Surgery, Istanbul, Turkey
  • Huseyin Kerem Tolan Health Science University, Umraniye Education and Research Hospital, Department of General Surgery, Istanbul, Turkey
  • Mustafa Ozbagriacik Health Science University, Umraniye Education and Research Hospital, Department of General Surgery, Istanbul, Turkey
  • Prof. Fikret Ezberci Health Science University, Umraniye Education and Research Hospital, Department of General Surgery, Istanbul, Turkey
October 11, 2019

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Introduction: We aimed to evaluate the diagnosis and treatment of breast cancer in women over 70 years.

Material & Methods: Patients who were operated due to breast cancer between January 2012 and January 2015 evaluated retrospectively. Patients were classified as Group 1 with patients aged 70 and over and Group 2 with patients under 70 years of age. For statistical analyses, χ2 and Mann–Whitney U tests were underwent (P<0.05).

Results: The study included 381 patients. Comorbidities were found in 156 patients. Of the patients, 53 aged 70 years and over (Group 1) and 328 under 70 years (Group 2). 48 patients of Group 1 and 143 patients of Group 2 underwent mastectomy and 5 patients of Group 1 and 185 patients of Group 2 underwent breast conserving surgery (P<0.0001).

Estrogen receptor was positive in 51 patients of Group 1 and in 313 patients of Group 2 (P= 0.79). The mean follow-up duration was 46 months. During follow-up, local or systemic metastasis or recurrence and mortality occurred in 4 and 2 patients in Group 1 and in 10 and 5 patient in Group 2, respectively.

Discussion: Age-related, breast cancer risk factors may also change. Treatment should be determined considering tumor characteristics and comorbidities in elderly patients with breast cancer. Thus, clinically, treatment strategies can be better identified. Surgical and oncologic treatment approaches do not differ in geriatric patients. Treatment options as well as surgical, chemotherapy and radiotherapy should be planned considering the patient's wishes, general condition and comorbidities.

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