Pharmacodermia after use of Anti-Inflammatory: A Case Report
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This case report aimed to show the interference of pharmacodermia in the increased use of anti-inflammatory drugs and evaluate the incidence of drug reactions in patients with evolution to cutaneous manifestations assuming multiple clinical aspects. An elderly patient on continuous use of bronchodilators, anticholinergics, and inhaled corticosteroids was hospitalized for pharmacodermia treatment after the use of anti-inflammatory drugs. The patient was admitted with a history of using Flancox (etodolac) for two days for low back pain, evolving suddenly with pruritic urticarial plaques in the trunk region, migrating to limbs and face. She mentioned being allergic to nimesulide, dipyrone, and penicillin during the anamnesis. The medication was immediately discontinued and intravenous corticosteroids (hydrocortisone 200 mg IV 8/8 h) were started associated with clinical support and antihistamine measures. The patient was discharged after seven days of hospitalization, with clinical improvement and remission of lesions. Corticosteroid suspension was prescribed with prednisone, Hixizine 25 mg, and promethazine.
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