A Rare Case of Behçet Disease Presenting with sepsis, Pulmonary Embolism and Right Ventricular Thrombus
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Behçet Disease is a chronic systemic inflammatory disorder that manifests as recurring mouth ulcers and a number of systemic symptoms, such as genital ulcers, eye disease, skin lesions, arthritis, genital warts and gastrointestinal, neurologic, or vascular disease. Both men and women are equally affected by it, and it is most frequent along the historic Silk Road, which runs from eastern Asia to the Mediterranean region. The majority of people begin to exhibit symptoms between the ages of 20 and 40. (1)
We describe a rare case of a 21-year-old man with two right ventricular masses and pulmonary embolism due to a not yet diagnosed Behçet’s disease.
Aksu T, Tufekcioglu O.: Intracardiac thrombus in Behçet's disease: four new cases and a comprehensive literature review. Rheumatol Int 2015; 35: pp. 1269-1279.
Kobayashi T, Kishimoto M, Swearingen CJ, et al. Differences in clinical manifestations, treatment, and concordance rates with two major sets of criteria for Behçet’s syndrome for patients in the US and Japan: data from a large, three-center cohort study. Mod Rheumatol 2013 May; 23(3):547–553
Davatchi F, Sadeghi Abdollahi B, Shahram F, et al. Validation of the International Criteria for Behçet’s disease (ICBD) in Iran. Int J Rheum Dis 2010;13(1):55–60
Kale A, Akyildiz L, Akdeniz N, Kale E. Pregnancy complicated by superior vena cava thrombosis and pulmonary embolism in a patient with Behcet disease and the use of heparin for treatment. Saudi Med J 2006;27(1):95–97
Hammami R, Abid L, Frikha F, et al. Intracardiac thrombus in a young man: don’t forget Behçet’s disease!. Intern Med 2012; 51(14):1865–1867
Aksu T, Tufekcioglu O.: Intracardiac thrombus in Behçet's disease: four new cases and a comprehensive literature review. Rheumatol Int 2015; 35: pp. 1269-1279.
Khammar Z, Berrady R, Boukhrissa A, et al. [Intracardiac thrombosis in Behçet disease: clinical presentation and outcome of three cases]. J Mal Vasc 2011;36(4):270–273
Yıldırım R, Dinler M, Yaşar Bilge NŞ, Kaşifoğlu T: A rarely seen manifestation in Behcet's disease: intracardiac thrombosis. Clin Rheumatol 2021; 40: pp. 4355-4356.
Piga M, Puchades F, Mayo I, D’Cruz D. Successful thrombolytic therapy for recurrent right ventricular thrombosis in Behçet’s disease. Clin Exp Rheumatol 2010;28(4, Suppl 60):S76–S78
Ozer N, Ciftçi O, Demirci M, et al. Right ventricular outflow tract thrombus in a case of Behcet’s disease. J Am Soc Echocardiogr 2005;18(4):380–382.
Houman M, Ksontini I, Ben Ghorbel I, et al. Association of right heart thrombosis, endomyocardial fibrosis, and pulmonary artery aneurysm in Behçet’s disease. Eur J Intern Med 2002; 13(7):455.
Gopathi S, Hurt RT, Guardiola J. Intracardiac thrombus in Behcet’s disease: a rare case in the United States. Respir Med CME 2011;4 (4):154–156.
Fekih M, Fennira S, Ghodbane L, Zaouali RM. [Intracardiac thrombosis: unusual complication of Behcet’s disease]. Tunis Med 2004; 82(8):785–790
Darie C, Knezinsky M, Demolombe-Rague S, et al. [Cardiac pseudotumor revealing Behçet’s disease]. Rev Med Interne 2005;26 (5):420–424
Kajiya T, Anan R, Kameko M, et al. Intracardiac thrombus, superior vena cava syndrome, and pulmonary embolism in a patient with Behçet’s disease: a case report and literature review. Heart Vessels 2007;22(4):278–283.
San Luis Miranda R, Lázaro Castillo JL, Enciso Gómez R, et al. [Right ventricular thrombus and pulmonary artery aneurysms in Behçet’s disease. Report of one case]. Arch Cardiol Mex 2007;77 (2):130–136
Emad Y, Abdel-Razek N, Gheita T, el-Wakd M, el-Gohary T, Samadoni A. Multislice CT pulmonary findings in Behçet’s disease (report of 16 cases). Clin Rheumatol 2007;26(6):879–884.
Sayin AG, Vural FS, Bozkurt AK, Oz B, Uygun N. Right atrial thrombus mimicking myxoma and bilateral pulmonary artery aneurysms in a patient with Behçet’s disease—a case report. Angiology 1993;44(11):915–918
Calvo-Romero JM, Lima-Rodríguez EM, Pérez-Miranda M, BureoDacal P. Low-grade and high-grade fever at presentation of acute pulmonary embolism. Blood Coagul Fibrinolysis 2004;15(4): 331–333.
Granel B, Berbis P, Serratrice J, Pelletier J, Disdier P, Weiller PJ. [An unusual cause of long-term fever: Behçet disease]. Presse Med 1999;28(40):2221–2222.
Alibaz-Oner F., et. al.: Behcet disease with vascular involvement: effects of different therapeutic regimens on the incidence of new relapses. Medicine 2015; 94: pp. e494.
Noureddine M, Charei N, Drighil A, Chraibi N. [Right intracardiac thrombus in Behçet’s disease]. Arch Mal Coeur Vaiss 2004;97 (9):925–928.
Espinosa G, Blanco I, Antón JM, Sánchez M, Macchiarini P, Barberà JA. Chronic thromboembolic pulmonary hypertension in Behçet’s disease: effectiveness of endarterectomy. Clin Exp Rheumatol 2010;28(4, Suppl 60):S79–S81.
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